In enzymology, a 4-chlorobenzoate—CoA ligase (EC 6.2.1.33) is an enzyme that catalyzes the chemical reaction 4-chlorobenzoate + CoA + ATP 4-chlorobenzoyl-CoA + AMP + diphosphate The 3 substrates of this enzyme are , CoA, and ATP, whereas its 3 products are , AMP, and diphosphate. This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 4-chlorobenzoate:CoA ligase. This enzyme participates in . It employs one cofactor, magnesium.
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