About: 3T3-L1

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3T3-L1 is a cell line derived from (mouse) 3T3 cells that is used in biological research on adipose tissue. 3T3-L1 cells have a fibroblast-like morphology, but, under appropriate conditions, the cells differentiate into an adipocyte-like phenotype. 3T3-L1 cells of the adipocyte morphology increase the synthesis and accumulation of triglycerides and acquire the signet ring appearance of adipose cells. These cells are also sensitive to lipogenic and lipolytic hormones, as well as drugs, including epinephrine, isoproterenol, and insulin.

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  • Buněčná linie 3T3-L1 je myší buněčná linie preadipocytů adherentního typu. Izolace této buněčné linie spočívala v klonování myších 3T3-L1 embryonálních fibroblastů, které ve velké míře akumulovaly lipidy ve formě tukových kapének . Tato linie je vysoce využívaná ve studiu molekulární biologie. Červené tukové kapénky produkované 3T3-L1 adipocyty obarvené roztokem Oil Red O. (cs)
  • 3T3-L1 is a cell line derived from (mouse) 3T3 cells that is used in biological research on adipose tissue. 3T3-L1 cells have a fibroblast-like morphology, but, under appropriate conditions, the cells differentiate into an adipocyte-like phenotype. 3T3-L1 cells of the adipocyte morphology increase the synthesis and accumulation of triglycerides and acquire the signet ring appearance of adipose cells. These cells are also sensitive to lipogenic and lipolytic hormones, as well as drugs, including epinephrine, isoproterenol, and insulin. (en)
  • 3T3-L1細胞系衍生自小鼠胚胎来源的NIH 3T3細胞系,有著成纖維細胞樣的形態,但在特定條件下,這些細胞會分化出脂肪細胞樣的表型。3T3-L1細胞對脂溶性激素和藥物敏感,包括腎上腺素、和胰島素等。3T3-L1細胞常用於脂肪組織的相關研究,其分化而來的脂肪樣細胞是脂肪細胞生物學研究中最常用的一個體外模型。 (zh)
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  • Buněčná linie 3T3-L1 je myší buněčná linie preadipocytů adherentního typu. Izolace této buněčné linie spočívala v klonování myších 3T3-L1 embryonálních fibroblastů, které ve velké míře akumulovaly lipidy ve formě tukových kapének . Tato linie je vysoce využívaná ve studiu molekulární biologie. Červené tukové kapénky produkované 3T3-L1 adipocyty obarvené roztokem Oil Red O. (cs)
  • 3T3-L1 is a cell line derived from (mouse) 3T3 cells that is used in biological research on adipose tissue. 3T3-L1 cells have a fibroblast-like morphology, but, under appropriate conditions, the cells differentiate into an adipocyte-like phenotype. 3T3-L1 cells of the adipocyte morphology increase the synthesis and accumulation of triglycerides and acquire the signet ring appearance of adipose cells. These cells are also sensitive to lipogenic and lipolytic hormones, as well as drugs, including epinephrine, isoproterenol, and insulin. (en)
  • 3T3-L1細胞系衍生自小鼠胚胎来源的NIH 3T3細胞系,有著成纖維細胞樣的形態,但在特定條件下,這些細胞會分化出脂肪細胞樣的表型。3T3-L1細胞對脂溶性激素和藥物敏感,包括腎上腺素、和胰島素等。3T3-L1細胞常用於脂肪組織的相關研究,其分化而來的脂肪樣細胞是脂肪細胞生物學研究中最常用的一個體外模型。 (zh)
rdfs:label
  • Buněčná linie 3T3-L1 (cs)
  • 3T3-L1 (en)
  • 3T3-L1 (zh)
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