About: 2001 Seattle Mariners season

The Seattle Mariners' 2001 season was the 25th since the franchise's inception. They finished with a 116–46 (.716) record, tying the major league record for wins set by the 1906 Chicago Cubs, and setting the record for wins by an American League team. Of those wins, 59 were by four or more runs, a record for the number of games won by such a margin. They also led the majors in both runs scored and fewest runs allowed. Despite the record-setting win total, the Mariners would not reach the postseason again until 2022, which was the longest active drought in the four major North American sports.