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In enzymology, a 2-oxoglutarate carboxylase (EC 6.4.1.7) is an enzyme that catalyzes the chemical reaction ATP + 2-oxoglutarate + HCO3- ADP + phosphate + oxalosuccinate The 3 substrates of this enzyme are ATP, 2-oxoglutarate, and HCO3-, whereas its 3 products are ADP, phosphate, and oxalosuccinate. This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is '. Other names in common use include oxalosuccinate synthetase', carboxylating factor for ICDH (incorrect), CFI, and OGC.

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  • In enzymology, a 2-oxoglutarate carboxylase (EC 6.4.1.7) is an enzyme that catalyzes the chemical reaction ATP + 2-oxoglutarate + HCO3- ADP + phosphate + oxalosuccinate The 3 substrates of this enzyme are ATP, 2-oxoglutarate, and HCO3-, whereas its 3 products are ADP, phosphate, and oxalosuccinate. This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is '. Other names in common use include oxalosuccinate synthetase', carboxylating factor for ICDH (incorrect), CFI, and OGC. (en)
  • La 2-oxoglutarato carboxilasa (EC 6.4.1.7) es una enzima que cataliza la reacción de carboxilación del 2-oxoglutarato a oxalosuccinato utilizando bicarbonato y ATP.​ 2-oxoglutarato + HCO3- + ATP oxalosuccinato + ADP + fosfato Requiere como cofactor biotina y magnesio. Originalmente se pensaba que esta enzima era un factor que promovía la carboxilación del 2-oxoglutarato por la isocitrato deshidrogenasa (NAD+), pero esta teoría fue rechazada. El producto de la reacción es inestable y es rápidamente convertido a isocitrato por la acción de la isocitrato deshidrogenasa (NAD+). La enzima del se presenta como un heterohexadecámero de 8 subunidades de cadena larga y 8 subunidades de cadena corta.​ (es)
  • 2-オキソグルタル酸カルボキシラーゼ(2-oxoglutarate carboxylase、EC 6.4.1.7)は、以下の化学反応を触媒する酵素である。 ATP + 2-オキソグルタル酸 + HCO3- ADP + リン酸 + オキサロコハク酸 従って、この酵素の基質は、ATPと2-オキソグルタル酸とHCO3-の3つ、生成物はADPとリン酸とオキサロコハク酸の3つである。 (ja)
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  • 6.4.1.7
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  • 6.400000 (xsd:double)
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  • 6 (xsd:integer)
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  • In enzymology, a 2-oxoglutarate carboxylase (EC 6.4.1.7) is an enzyme that catalyzes the chemical reaction ATP + 2-oxoglutarate + HCO3- ADP + phosphate + oxalosuccinate The 3 substrates of this enzyme are ATP, 2-oxoglutarate, and HCO3-, whereas its 3 products are ADP, phosphate, and oxalosuccinate. This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is '. Other names in common use include oxalosuccinate synthetase', carboxylating factor for ICDH (incorrect), CFI, and OGC. (en)
  • 2-オキソグルタル酸カルボキシラーゼ(2-oxoglutarate carboxylase、EC 6.4.1.7)は、以下の化学反応を触媒する酵素である。 ATP + 2-オキソグルタル酸 + HCO3- ADP + リン酸 + オキサロコハク酸 従って、この酵素の基質は、ATPと2-オキソグルタル酸とHCO3-の3つ、生成物はADPとリン酸とオキサロコハク酸の3つである。 (ja)
  • La 2-oxoglutarato carboxilasa (EC 6.4.1.7) es una enzima que cataliza la reacción de carboxilación del 2-oxoglutarato a oxalosuccinato utilizando bicarbonato y ATP.​ 2-oxoglutarato + HCO3- + ATP oxalosuccinato + ADP + fosfato (es)
rdfs:label
  • 2-oxoglutarate carboxylase (en)
  • 2-oxoglutarato carboxilasa (es)
  • 2-オキソグルタル酸カルボキシラーゼ (ja)
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  • 2-Oxoglutarate carboxylase (en)
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