Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.

Property Value
dbo:abstract
  • Le thiocolchicoside est un dérivé semi-synthétique de la colchicine, il est utilisé comme médicament myorelaxant, sous les noms commerciaux Coltramyl et Miorel, par exemple. (fr)
  • Il tiocolchicoside è una molecola solforata semisintetica derivata dal colchicoside, un glucoside prodotto dal colchico. Ha effetto miorilassante e antinfiammatorio. Viene utilizzato per il trattamento delle contratture muscolare viene spesso somministrato mediante compresse da 4 mg. (it)
  • Tiocolchicósido é um fármaco utilizado pela medicina como miorrelaxante. (pt)
  • Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals. (en)
dbo:atcPrefix
  • M03
dbo:atcSuffix
  • BX05
dbo:bioavailability
  • 25.000000 (xsd:float)
dbo:casNumber
  • 602-41-5
dbo:fdaUniiCode
  • T1X8S697GT
dbo:iupacName
  • N-[(7S)-3-(β-(D)-Glucopyranosyloxy)-1,2-dimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (en)
dbo:pubchem
  • 72067
dbo:thumbnail
dbo:wikiPageID
  • 12637230 (xsd:integer)
dbo:wikiPageRevisionID
  • 679099417 (xsd:integer)
dbp:atcPrefix
  • M03 (en)
dbp:atcSuffix
  • BX05 (en)
dbp:bioavailability
  • 25.0
dbp:c
  • 27 (xsd:integer)
dbp:casNumber
  • 602 (xsd:integer)
dbp:chembl
  • 1705373 (xsd:integer)
dbp:eliminationHalfLife
  • -21600.0
dbp:h
  • 33 (xsd:integer)
dbp:iupacName
  • N-[-3--1,2-dimethoxy-10--9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (en)
dbp:kegg
  • D07276 (en)
dbp:legalStatus
  • Rx-only (en)
dbp:molecularWeight
  • 563.618000 (xsd:double)
dbp:n
  • 1 (xsd:integer)
dbp:o
  • 10 (xsd:integer)
dbp:pubchem
  • 72067 (xsd:integer)
dbp:routesOfAdministration
dbp:s
  • 1 (xsd:integer)
dbp:smiles
  • O=CC (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • LEQAKWQJCITZNK-MSQQGMGVSA-N (en)
dbp:unii
  • T1X8S697GT (en)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 448013724 (xsd:integer)
dbp:watchedfields
  • changed (en)
dct:subject
rdf:type
rdfs:comment
  • Le thiocolchicoside est un dérivé semi-synthétique de la colchicine, il est utilisé comme médicament myorelaxant, sous les noms commerciaux Coltramyl et Miorel, par exemple. (fr)
  • Il tiocolchicoside è una molecola solforata semisintetica derivata dal colchicoside, un glucoside prodotto dal colchico. Ha effetto miorilassante e antinfiammatorio. Viene utilizzato per il trattamento delle contratture muscolare viene spesso somministrato mediante compresse da 4 mg. (it)
  • Tiocolchicósido é um fármaco utilizado pela medicina como miorrelaxante. (pt)
  • Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals. (en)
rdfs:label
  • Thiocolchicoside (fr)
  • Tiocolchicoside (it)
  • Thiocolchicoside (en)
  • Tiocolchicósido (pt)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is foaf:primaryTopic of