Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.

Property Value
dbo:abstract
  • Le thiocolchicoside est un dérivé semi-synthétique de la colchicine, il est utilisé comme médicament myorelaxant, sous les noms commerciaux Coltramyl et Miorel, par exemple. (fr)
  • Il tiocolchicoside è una molecola solforata semisintetica derivata dal colchicoside, un glucoside prodotto dal colchico. Ha effetto miorilassante e antinfiammatorio. Viene utilizzato per il trattamento delle contratture muscolare e viene spesso somministrato mediante compresse da 4 mg. (it)
  • Tiocolchicósido é um fármaco utilizado pela medicina como miorrelaxante. (pt)
  • Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals. (en)
dbo:atcPrefix
  • M03
dbo:atcSuffix
  • BX05
dbo:bioavailability
  • 25.000000 (xsd:float)
dbo:casNumber
  • 602-41-5
dbo:fdaUniiCode
  • T1X8S697GT
dbo:iupacName
  • N-[(7S)-3-(β-(D)-Glucopyranosyloxy)-1,2-dimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]ethanamide (en)
dbo:pubchem
  • 72067
dbo:thumbnail
dbo:wikiPageID
  • 12637230 (xsd:integer)
dbo:wikiPageRevisionID
  • 706813888 (xsd:integer)
dbp:atcPrefix
  • M03 (en)
dbp:atcSuffix
  • BX05 (en)
dbp:bioavailability
  • 25.0
dbp:casNumber
  • 602 (xsd:integer)
dbp:iupacName
  • N-[-3--1,2-dimethoxy-10--9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]ethanamide (en)
dbp:pubchem
  • 72067 (xsd:integer)
dbp:unii
  • T1X8S697GT (en)
dct:subject
rdf:type
rdfs:comment
  • Le thiocolchicoside est un dérivé semi-synthétique de la colchicine, il est utilisé comme médicament myorelaxant, sous les noms commerciaux Coltramyl et Miorel, par exemple. (fr)
  • Il tiocolchicoside è una molecola solforata semisintetica derivata dal colchicoside, un glucoside prodotto dal colchico. Ha effetto miorilassante e antinfiammatorio. Viene utilizzato per il trattamento delle contratture muscolare e viene spesso somministrato mediante compresse da 4 mg. (it)
  • Tiocolchicósido é um fármaco utilizado pela medicina como miorrelaxante. (pt)
  • Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals. (en)
rdfs:label
  • Thiocolchicoside (fr)
  • Tiocolchicoside (it)
  • Thiocolchicoside (en)
  • Tiocolchicósido (pt)
owl:sameAs
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