Rho(D) immune globulin or Rh0(D) immune globulin (letter o and digit zero are both widely attested; more at Rh blood group system > Rh nomenclature) is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). It is sold under various brand names.

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dbpedia-owl:abstract
  • Rho(D) immune globulin or Rh0(D) immune globulin (letter o and digit zero are both widely attested; more at Rh blood group system > Rh nomenclature) is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). It is sold under various brand names. The medicine is a solution of IgG anti-D (anti-RhD) antibodies that take out any fetal RhD-positive erythrocytes which have entered the maternal blood stream from fetal circulation, before maternal immune system can react to them, thus preventing maternal sensitazation. In a Rhesus-negative mother, Rho(D) immune globulin can prevent temporary sensitization of the maternal immune system to Rh D antigens, which can cause rhesus disease in the current or in subsequent pregnancies. With the widespread use of Rho(D) immune globulin, Rh disease of the fetus and newborn has almost disappeared. The risk that a D-negative mother can be alloimmunized by a D-positive fetus can be reduced from approximately 16% to less than 0.1% by the appropriate administration of RhIG.,Rho(D) immune globulin is composed of IgG antibodies and therefore is able to cross the placenta. In rare cases this can cause a baby to have a weakly positive DAT (direct antiglobulin test) due to sensitization of fetal cells from mothers who have received multiple doses of Rho(D) Immune Globulin. However, no treatment is necessary as the clinical course is benign.It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
  • Les immunoglobulines humaines anti-Rho (D) sont un médicament dérivé du sang, c’est-à-dire préparé à partir du sang de donneurs, utilisé pour prévenir la sensibilisation maternelle à l'antigène Rhésus D (RH1) présent à la surface des érythrocytes du fœtus (c'est-à-dire pour prévenir la maladie hémolytique du nouveau-né). C'est une solution d'IgG anti-D, (anti-RH1) qui se lie aux cellules Rh positives fœtales présentes dans la circulation maternelle. Cela prévient l'activation des lymphocytes B et la formation de cellules mémoire, et donc l'immunisation.Il y a actuellement des recherches sur la production d'anti-D chez des plantes transgéniques.
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  • RhoGAM, [[#Brand names
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  • Rho(D) immune globulin or Rh0(D) immune globulin (letter o and digit zero are both widely attested; more at Rh blood group system > Rh nomenclature) is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). It is sold under various brand names.
  • Les immunoglobulines humaines anti-Rho (D) sont un médicament dérivé du sang, c’est-à-dire préparé à partir du sang de donneurs, utilisé pour prévenir la sensibilisation maternelle à l'antigène Rhésus D (RH1) présent à la surface des érythrocytes du fœtus (c'est-à-dire pour prévenir la maladie hémolytique du nouveau-né). C'est une solution d'IgG anti-D, (anti-RH1) qui se lie aux cellules Rh positives fœtales présentes dans la circulation maternelle.
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  • Rho(D) immune globulin
  • Immunoglobuline anti-D
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  • Rho(D) immune globulin
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