Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid family. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex and Gambaran. It is used to treat pain or inflammation caused by arthritis. Nabumetone works by reducing the effects of hormones that cause pain and inflammation. It has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAIDs.
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- 4-(6-methoxy-2-naphthyl)-2-butanone
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- 4-(6-methoxy-2-naphthyl)-2-butanone
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- Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid family. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex and Gambaran. It is used to treat pain or inflammation caused by arthritis. Nabumetone works by reducing the effects of hormones that cause pain and inflammation. It has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAIDs.
- Nabumeton ist ein Arzneistoff, der als Prodrug erst durch metabolische Umwandlung in der Leber zum aktiven Wirkstoff 6-Methoxy-2-naphthylessigsäure (6-MNA) wird. Dieser gehört zur Gruppe der nichtsteriodalen Antirheumatika, welche zur symptomatischen Behandlung von entzündlichen und degenerativen rheumatischen Erkrankungen eingesetzt werden.
- Nabumeton – lek z grupy niesterydowych przeciwzapalnych, mający zdolność względnie wybiórczego hamowania cykloksygenazy COX-2 mający działanie przeciwzapalne, przeciwbólowe i przeciwgorączkowe. Jest uważany za lek względnie bezpieczny, rzadko powoduje uszkodzenia błony śluzowej żołądka, co związane jest (oprócz powyższego preferencyjnego blokowania COX-2) z jego wchłanianiem w niezmienionej postaci i dopiero następnym metabolizmem "pierwszego przejścia" przez wątrobę, do aktywnego kwasu 6-metoksy-2-naftylooctowego (6-MNA).
- Nabumetona é um fármaco utilizado como anti-inflamatório, antipirético e analgésico, do grupo dos antiinflamatórios não estereoidais. Em seu estado bruto é um sólido insolúvel em água.
- Nabumeton (handelsnamn Refilex) är ett så kallat NSAID-läkemedel (från engelskans non-steriod-antiinflammatory-drugs) som främst används mot smärta och stelhet vid artros.
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- 23 hours (active metabolite)
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- 4-(6-methoxy-2-naphthyl)-2-butanone
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- Hepatic, to active metabolite 6-methoxy-2-naphthylacetic acid; 6-MNA
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- > 99% (active metabolite)
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- Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid family. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex and Gambaran. It is used to treat pain or inflammation caused by arthritis. Nabumetone works by reducing the effects of hormones that cause pain and inflammation. It has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAIDs.
- Nabumeton ist ein Arzneistoff, der als Prodrug erst durch metabolische Umwandlung in der Leber zum aktiven Wirkstoff 6-Methoxy-2-naphthylessigsäure (6-MNA) wird. Dieser gehört zur Gruppe der nichtsteriodalen Antirheumatika, welche zur symptomatischen Behandlung von entzündlichen und degenerativen rheumatischen Erkrankungen eingesetzt werden.
- Nabumeton – lek z grupy niesterydowych przeciwzapalnych, mający zdolność względnie wybiórczego hamowania cykloksygenazy COX-2 mający działanie przeciwzapalne, przeciwbólowe i przeciwgorączkowe.
- Nabumetona é um fármaco utilizado como anti-inflamatório, antipirético e analgésico, do grupo dos antiinflamatórios não estereoidais. Em seu estado bruto é um sólido insolúvel em água.
- Nabumeton (handelsnamn Refilex) är ett så kallat NSAID-läkemedel (från engelskans non-steriod-antiinflammatory-drugs) som främst används mot smärta och stelhet vid artros.
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- Nabumetone
- Nabumeton
- Nabumeton
- Nabumetona
- Nabumeton
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