Ketotifen is a second-generation H1-antihistamine and mast cell stabilizer. It is most commonly sold in as a salt of Fumaric Acid, Ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds.

PropertyValue
dbpedia-owl:abstract
  • Ketotifen is a second-generation H1-antihistamine and mast cell stabilizer. It is most commonly sold in as a salt of Fumaric Acid, Ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds. The drug is marketed as ophthalmic solutions under the brand names Zaditor/Zaditen (Novartis), Alaway (Bausch and Lomb), Zyrtec Itchy-Eye Drops, and Claritin Eye. A generic version of Novartis' Zaditor, ketotifen fumarate ophthalmic solution, 0.025%, is available from Perrigo and distributed as store brands.
  • Il ketotifene è un farmaco antiasmatico antistaminico di seconda generazione, molto utilizzato in pediatria, con un ampio spettro di azioni farmacologiche.
  • Ketotifen – organiczny związek chemiczny, lek przeciwhistaminowy I generacji, antagonista receptora H1. W dawkach wyższych niż terapeutyczne stabilizuje błony komórkowe mastocytów, hamuje ich degranulację i tym samym uwalnianie z ich ziarnistości histaminy i innych przekaźników reakcji alergicznych.
  • Cetotifeno (fumarato) é um fármaco anti-histamínico utilizado no tratamento de alergias, como rinites, conjutivites e profilaxia de crises de asma. Tem afinidade para receptores H1 da histamina e inibe também leucotrienos
  • Кетотифен — лекарственное средство, стабилизатор мембран тучных клеток, обладает умеренной H1-гистаминоблокирующей активностью
  • La kétotifène est une substance chimique employée comme antagoniste des récepteurs H1 de l'histamine. Elle est utilisée dans le traitement de l'allergie, de l'asthme, du rhume des foins et de l'angiœdème. Elle est commercialisée sous forme de fumarate de kétofène.
dbpedia-owl:atcPrefix
  • R06
dbpedia-owl:atcSuffix
  • AX17
dbpedia-owl:casNumber
  • 34580-14-8
dbpedia-owl:drugbank
  • APRD01061
dbpedia-owl:iupacName
  • 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo4,5cyclohepta1,2-bthiophen-10-one
dbpedia-owl:pubchem
  • 3827
dbpedia-owl:thumbnail
dbpedia-owl:wikiPageExternalLink
dbpprop:atcPrefix
  • R06
dbpprop:atcSuffix
  • AX17
dbpprop:bioavailability
  • 60 (xsd:integer)
dbpprop:c
  • 19 (xsd:integer)
dbpprop:casNumber
  • 34580 (xsd:integer)
dbpprop:chembl
  • 534 (xsd:integer)
dbpprop:chemspiderid
  • 3695 (xsd:integer)
dbpprop:drugbank
  • APRD01061
dbpprop:eliminationHalfLife
  • 12 (xsd:integer)
dbpprop:h
  • 19 (xsd:integer)
dbpprop:inchi
  • 1 (xsd:integer)
dbpprop:inchikey
  • ZCVMWBYGMWKGHF-UHFFFAOYAW
dbpprop:iupacName
  • 4 (xsd:integer)
dbpprop:kegg
  • D01332
dbpprop:legalStatus
  • Oral - Prescription, Eye Drops - OTC
dbpprop:legalUs
  • OTC
dbpprop:metabolism
  • Hepatic
dbpprop:molecularWeight
  • 309 (xsd:integer)
dbpprop:n
  • 1 (xsd:integer)
dbpprop:o
  • 1 (xsd:integer)
dbpprop:pregnancyUs
  • C
dbpprop:proteinBound
  • 75 (xsd:integer)
dbpprop:pubchem
  • 3827 (xsd:integer)
dbpprop:routesOfAdministration
  • Oral, Eye Drops
dbpprop:s
  • 1 (xsd:integer)
dbpprop:smiles
  • 1.0
dbpprop:unii
  • HBD503WORO
dbpprop:verifiedfields
  • changed
dbpprop:verifiedrevid
  • 394169709 (xsd:integer)
dbpprop:width
  • 200 (xsd:integer)
dbpprop:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Il ketotifene è un farmaco antiasmatico antistaminico di seconda generazione, molto utilizzato in pediatria, con un ampio spettro di azioni farmacologiche.
  • Ketotifen – organiczny związek chemiczny, lek przeciwhistaminowy I generacji, antagonista receptora H1. W dawkach wyższych niż terapeutyczne stabilizuje błony komórkowe mastocytów, hamuje ich degranulację i tym samym uwalnianie z ich ziarnistości histaminy i innych przekaźników reakcji alergicznych.
  • Cetotifeno (fumarato) é um fármaco anti-histamínico utilizado no tratamento de alergias, como rinites, conjutivites e profilaxia de crises de asma. Tem afinidade para receptores H1 da histamina e inibe também leucotrienos
  • Кетотифен — лекарственное средство, стабилизатор мембран тучных клеток, обладает умеренной H1-гистаминоблокирующей активностью
  • Ketotifen is a second-generation H1-antihistamine and mast cell stabilizer. It is most commonly sold in as a salt of Fumaric Acid, Ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds.
  • La kétotifène est une substance chimique employée comme antagoniste des récepteurs H1 de l'histamine. Elle est utilisée dans le traitement de l'allergie, de l'asthme, du rhume des foins et de l'angiœdème. Elle est commercialisée sous forme de fumarate de kétofène.
rdfs:label
  • Ketotifene
  • Kétotifène
  • Ketotifen
  • Ketotifen
  • Cetotifeno
  • Кетотифен
owl:sameAs
foaf:depiction
foaf:page
is dbpedia-owl:wikiPageRedirects of
is owl:sameAs of
is foaf:primaryTopic of