The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. The κ-opioid receptor is a type of opioid receptor that binds the opioid peptide dynorphin as the primary endogenous ligand.

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  • The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. The κ-opioid receptor is a type of opioid receptor that binds the opioid peptide dynorphin as the primary endogenous ligand. In addition to dynorphin, a variety of natural alkaloids and synthetic ligands bind to the receptor. The κ-opioid receptor may provide a natural addiction control mechanism, and consequently selective agonists of this receptor may have therapeutic potential in the treatment of addiction.
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  • 4986
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  • The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. The κ-opioid receptor is a type of opioid receptor that binds the opioid peptide dynorphin as the primary endogenous ligand.
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  • Kappa Opioid receptor
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