John W. Holter (April 1, 1916 - December 22, 2003) was a toolmaker working for the Yale and Town Lock Company Stamford Connecticut. His son Charles Case "Casey" Holter was born on November 7, 1955 with a severe form of spina bifida. Shortly after birth he contracted meningitis, which caused his head to expand rapidly. His parents were told that he had developed "water on the brain" or hydrocephalus.
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- John Holter oli yhdysvaltalaisessa lukkotehtaassa työskennellyt mies, jonka pojalla Charles Case "Casey" Holterilla oli syntyessään 7. marraskuuta 1955 vakava spina bifida. Pian syntymän jälkeen hän sai aivokalvontulehduksen, ja hänen päänsä laajeni nopeasti. Vanhemmille ilmoitettaan, että hänelle oli muodostonut "vettä aivoihin" eli hydrokefalus. Onneksi Holterin poikaa hoidettiin Philadelphiassa, sillä kirurgit Spitz ja Nulsen olivat jo esitelleet menetelmän, jolla neste voidaan saada pois aivoista. Tarvittiin vain halpa ja kätevä läppä, joka pitäisi virtauksen suunnan oikeana ja aivopaineen normaalina. Holter huomasi sattumalta, että silikonista valmistettu yksisuuntainen venttiili olisi käyttökelpoinen. Sitä ennen oli jo tehty yksi yritys, jossa potilaana ollut poika kuoli. Kun laitetta oli kehitetty sopivaksi lääketieteelliseen käyttöön, se patentoitiin. Tohtori Spitz ja John Holter perustivat sunttien valmistamiseen yrityksen. Vaikka Holter oma poika poika ehti saada parantumattoman vamman ja kuoli muutaman vuoden kuluttua, laite on 1950-luvun jälkeen auttanut lukemattomia lapsia.
- John W. Holter (April 1, 1916 - December 22, 2003) was a toolmaker working for the Yale and Town Lock Company Stamford Connecticut. His son Charles Case "Casey" Holter was born on November 7, 1955 with a severe form of spina bifida. Shortly after birth he contracted meningitis, which caused his head to expand rapidly. His parents were told that he had developed "water on the brain" or hydrocephalus. As luck would have it Holter's son was being looked after in Philadelphia, where the surgeons Nulsen and Spitz had already demonstrated that a ventricle-to-atrium diversion system could work. What they needed was an inexpensive and practical valve that could control the direction of the flow and maintain normal cranial pressure. A chance discovery showed Holter, after a failed attempt in which a young boy died, that he could use a silicone one-way valve (pressure sealing). After a medically suitable grade of Silastic was found, the device was patented, and John Holter set up a company, Holter-Hausner International, to manufacture the cerebral shunts. Although he was unable to save his son Casey, his design, the Spitz-Holter valve (also called the Spitz-Holter shunt) continues to help millions around the world since the late 1950s.
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- 2003-01-01 00:00:00 (xsd:date)
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- Holter, John
- John W. Holter, DSc, CBE
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- John Holter oli yhdysvaltalaisessa lukkotehtaassa työskennellyt mies, jonka pojalla Charles Case "Casey" Holterilla oli syntyessään 7. marraskuuta 1955 vakava spina bifida. Pian syntymän jälkeen hän sai aivokalvontulehduksen, ja hänen päänsä laajeni nopeasti. Vanhemmille ilmoitettaan, että hänelle oli muodostonut "vettä aivoihin" eli hydrokefalus.
- John W. Holter (April 1, 1916 - December 22, 2003) was a toolmaker working for the Yale and Town Lock Company Stamford Connecticut. His son Charles Case "Casey" Holter was born on November 7, 1955 with a severe form of spina bifida. Shortly after birth he contracted meningitis, which caused his head to expand rapidly. His parents were told that he had developed "water on the brain" or hydrocephalus.
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- John W. Holter, DSc, CBE
- John Holter
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