Shifts in site-specific evolutionary rates over time. In the field of molecular evolution, the principle of heterotachy states that the substitution rate of sites in a gene can change through time . It has been proposed that the positions that show switches in substitution rate over time --i.e. , heterotachous sites-- are good indicators of functional divergence.
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- Shifts in site-specific evolutionary rates over time. In the field of molecular evolution, the principle of heterotachy states that the substitution rate of sites in a gene can change through time . It has been proposed that the positions that show switches in substitution rate over time --i.e. , heterotachous sites-- are good indicators of functional divergence. However, it appears that heterotachy is a much more general process, since most variable sites of homologous proteins with no evidence of functional shift are heterotachous.
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- Shifts in site-specific evolutionary rates over time. In the field of molecular evolution, the principle of heterotachy states that the substitution rate of sites in a gene can change through time . It has been proposed that the positions that show switches in substitution rate over time --i.e. , heterotachous sites-- are good indicators of functional divergence.
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