Dystroglycan is a protein that in humans is encoded by the DAG1 gene. Dystroglycan is one of the dystrophin-associated glycoproteins, which is encoded by a 5.5 kb transcript in Homo sapiens by chromosome 3. There are two exons that are separated by a large intron. The spliced exons codes for a protein product is finally cleaved into two non-covalently associated subunits, [alpha alpha] (N-terminal) and [beta beta] (C-terminal).
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- El distroglicano es un receptor celular que organiza la unión entre la laminina de la matriz extracelular y la distrofina que se enlaza con citoesqueleto. Fue aislado originalmente del músculo esquelético, donde se propuso el nombre de distroglicano por su asociación a distrofina y por su glicosilación extensiva. El distroglicano esta conformado dos subunidades denominadas α-distroglicano y β-distroglicano. El α-distroglicano esta glicosilado en la membrana e interacciona con laminina-2. El β-distroglicano es una glicoproteína de membrana que puede unirse a distrofina o su homologo utrofina mediante su extremo carboxilo terminal.
- Dystroglycan is a protein that in humans is encoded by the DAG1 gene. Dystroglycan is one of the dystrophin-associated glycoproteins, which is encoded by a 5.5 kb transcript in Homo sapiens by chromosome 3. There are two exons that are separated by a large intron. The spliced exons codes for a protein product is finally cleaved into two non-covalently associated subunits, [alpha alpha] (N-terminal) and [beta beta] (C-terminal).
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- Dystroglycan is a protein that in humans is encoded by the DAG1 gene. Dystroglycan is one of the dystrophin-associated glycoproteins, which is encoded by a 5.5 kb transcript in Homo sapiens by chromosome 3. There are two exons that are separated by a large intron. The spliced exons codes for a protein product is finally cleaved into two non-covalently associated subunits, [alpha alpha] (N-terminal) and [beta beta] (C-terminal).
- El distroglicano es un receptor celular que organiza la unión entre la laminina de la matriz extracelular y la distrofina que se enlaza con citoesqueleto. Fue aislado originalmente del músculo esquelético, donde se propuso el nombre de distroglicano por su asociación a distrofina y por su glicosilación extensiva. El distroglicano esta conformado dos subunidades denominadas α-distroglicano y β-distroglicano. El α-distroglicano esta glicosilado en la membrana e interacciona con laminina-2.
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- Distroglicano
- Dystroglycan
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