A drug allergy is an allergy to a drug, most commonly a medication. Medical attention should be sought immediately if an allergic reaction is suspected. An allergic reaction will not occur on the first exposure to a substance. The first exposure allows the body to create antibodies and memory lymphocyte cells for the antigen. However, drugs often contain many different substances, including dyes, which could cause allergic reactions.
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- A drug allergy is an allergy to a drug, most commonly a medication. Medical attention should be sought immediately if an allergic reaction is suspected. An allergic reaction will not occur on the first exposure to a substance. The first exposure allows the body to create antibodies and memory lymphocyte cells for the antigen. However, drugs often contain many different substances, including dyes, which could cause allergic reactions. This can cause an allergic reaction on the first administration of a drug. For example, a person who developed an allergy to a red dye will be allergic to any new drug which contains that red dye. A drug allergy is different from an intolerance. A drug intolerance, which is often a milder, non-immune-mediated reaction, does not depend on prior exposure. Most people who believe they are allergic to aspirin are actually suffering from a drug intolerance.
- 薬物アレルギー(やくぶつあれるぎー、英:drug allergy)とは薬によって生じるアレルギーの総称。薬物アレルギーは。抗菌薬や解熱剤などの医薬品により生じやすい。一般に医薬品は低分子のものが多いため、それ自体が抗原とはならず、生体内のタンパク質などの高分子と結合することにより、抗原性を有するアレルゲンとなる。理論的には2回目以降の投与の際に発現し、投与量に関係なく、その症状は薬の薬理作用と関係なく、その薬の拮抗薬で症状は緩和されない。また、薬物アレルギーを起こしやすい個体でのみ発生する。抗菌薬の初回投与の際にアレルギーが発現する場合があるが、これはその抗菌薬の残留した食品の摂取あるいは化学構造の類似した薬物の投与が原因であると考えられている。
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- A drug allergy is an allergy to a drug, most commonly a medication. Medical attention should be sought immediately if an allergic reaction is suspected. An allergic reaction will not occur on the first exposure to a substance. The first exposure allows the body to create antibodies and memory lymphocyte cells for the antigen. However, drugs often contain many different substances, including dyes, which could cause allergic reactions.
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