The dopamine receptor D4 is a G protein-coupled receptor encoded by the DRD4 gene. As with other dopamine receptor subtypes, the D4 receptor is activated by the neurotransmitter dopamine. It is linked to many neurological and psychiatric conditions including schizophrenia, Parkinsons disease, bipolar disorder, addictive behaviors, and eating disorders such as anorexia nervosa, bulimia nervosa and binge eating. It is also a target for drugs which treat schizophrenia and Parkinson disease.
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- The dopamine receptor D4 is a G protein-coupled receptor encoded by the DRD4 gene. As with other dopamine receptor subtypes, the D4 receptor is activated by the neurotransmitter dopamine. It is linked to many neurological and psychiatric conditions including schizophrenia, Parkinsons disease, bipolar disorder, addictive behaviors, and eating disorders such as anorexia nervosa, bulimia nervosa and binge eating. It is also a target for drugs which treat schizophrenia and Parkinson disease. The D4 receptor is considered to be D2-like in which the activated receptor inhibits the enzyme adenylate cyclase, thereby reducing the intracellular concentration of the second messenger cyclic AMP.
- O receptor D4 de dopamina é um receptor acoplado à proteína G, codificado pelo gene Predefinição:Gene. Tal como outros tipos de receptores de dopamina, o receptor D4 é activado pelo neurotransmissor dopamina. É também um alvo para drogas que tratam a esquizofrenia e a doença de Parkinson. O receptor D4 é considerado um receptor do tipo D2, no qual o receptor activado inibe a enzima adenilato ciclase, reduzindo assim a concentração intracelular do mensageiro secundário AMP cíclico.
- Дофаминовый рецептор D4 - D2-подобный рецептор дофамина, сопряжённый с G-белками. Подобно D2-рецептору, способен связывать антипсихотические препараты. Вариации гена связывают с различными поведенческими фенотипами и расстройствами, в том числе с дисфункцией вегетативной нервной системы, СДВГ, шизофренией, и склонностью к поиску новизны.
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- O receptor D4 de dopamina é um receptor acoplado à proteína G, codificado pelo gene Predefinição:Gene. Tal como outros tipos de receptores de dopamina, o receptor D4 é activado pelo neurotransmissor dopamina. É também um alvo para drogas que tratam a esquizofrenia e a doença de Parkinson. O receptor D4 é considerado um receptor do tipo D2, no qual o receptor activado inibe a enzima adenilato ciclase, reduzindo assim a concentração intracelular do mensageiro secundário AMP cíclico.
- Дофаминовый рецептор D4 - D2-подобный рецептор дофамина, сопряжённый с G-белками. Подобно D2-рецептору, способен связывать антипсихотические препараты. Вариации гена связывают с различными поведенческими фенотипами и расстройствами, в том числе с дисфункцией вегетативной нервной системы, СДВГ, шизофренией, и склонностью к поиску новизны.
- The dopamine receptor D4 is a G protein-coupled receptor encoded by the DRD4 gene. As with other dopamine receptor subtypes, the D4 receptor is activated by the neurotransmitter dopamine. It is linked to many neurological and psychiatric conditions including schizophrenia, Parkinsons disease, bipolar disorder, addictive behaviors, and eating disorders such as anorexia nervosa, bulimia nervosa and binge eating. It is also a target for drugs which treat schizophrenia and Parkinson disease.
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- Dopamine receptor D4
- Receptor D4 de dopamina
- Дофаминовый рецептор D4
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