Stereoisomeric Dexmethylphenidate (sold commercially by Novartis as Focalin, also available generically in the US exclusively from Teva) is a pharmaceutical drug used to treat ADHD. It is a psychostimulant DRI that affects the CNS. Dexmethylphenidate has a 4-6 hour duration of effect (a long-acting formulation, Focalin XR, which spans 12 hours is also available and has been shown to be as effective as racemic d,l-methylphenidate XR, with flexible dosing and good tolerability.

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  • N06
dbpedia-owl:Drug/atcSuffix
  • BA04
dbpedia-owl:Drug/casNumber
  • 40431-64-9
dbpedia-owl:Drug/drugbank
  • APRD00657
dbpedia-owl:Drug/iupacName
  • (R,R)-(+)-Methyl 2-phenyl-2-(2-piperidyl)acetate
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  • 4158
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  • N06
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  • BA04
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  • 40431-64-9
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  • APRD00657
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  • (R,R)-(+)-Methyl 2-phenyl-2-(2-piperidyl)acetate
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  • 4158
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dbpprop:abstract
  • Stereoisomeric Dexmethylphenidate (sold commercially by Novartis as Focalin, also available generically in the US exclusively from Teva) is a pharmaceutical drug used to treat ADHD. It is a psychostimulant DRI that affects the CNS. Dexmethylphenidate has a 4-6 hour duration of effect (a long-acting formulation, Focalin XR, which spans 12 hours is also available and has been shown to be as effective as racemic d,l-methylphenidate XR, with flexible dosing and good tolerability. ) It has also been demonstrated to reduce the symptoms of childhood ADHD, as well as ADHD in adults. Dexmethylphenidate has a similar side-effect profile to methylphenidate and can be administered without regard to food intake.
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  • N06
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  • BA04
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  • 11 – 52%
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  • 14 (xsd:integer)
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  • 40431-64-9
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  • APRD00657
dbpprop:eliminationHalfLife
  • 2 – 4 hours
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  • 19 (xsd:integer)
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  • Dextromethylphenidate-based-on-hydrochloride-xtal-1995-3D-balls.png
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  • R,R)-(+)-Methyl 2-phenyl-2-(2-piperidyl)acetate
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  • Schedule 8
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  • Schedule III
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  • Class B
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  • Schedule II
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  • 233.31 g/mol
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  • oral
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  • Stereoisomeric Dexmethylphenidate (sold commercially by Novartis as Focalin, also available generically in the US exclusively from Teva) is a pharmaceutical drug used to treat ADHD. It is a psychostimulant DRI that affects the CNS. Dexmethylphenidate has a 4-6 hour duration of effect (a long-acting formulation, Focalin XR, which spans 12 hours is also available and has been shown to be as effective as racemic d,l-methylphenidate XR, with flexible dosing and good tolerability.
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  • Dexmethylphenidate
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