In collagen, the collagen helix, or type 2 helix, is a major shape in secondary structure. It consists of a triple helix made of the repetitious amino acid sequence glycine - proline - hydroxyproline. Each of the three chains is stabilized by the steric repulsion due to the pyrrolidone rings of proline and hydroxyproline residues.
| Property | Value |
| dbpedia-owl:thumbnail
| |
| dbpprop:abstract
|
- In collagen, the collagen helix, or type 2 helix, is a major shape in secondary structure. It consists of a triple helix made of the repetitious amino acid sequence glycine - proline - hydroxyproline. Each of the three chains is stabilized by the steric repulsion due to the pyrrolidone rings of proline and hydroxyproline residues. The pyrrolidone rings keep out of each other’s way when the polypeptide chain assumes this extended helical form, which is much more open than the tightly coiled form of the alpha helix. The three chains are hydrogen bonded to each other. The hydrogen bond donors are the peptide NH groups of glycine residues. The hydrogen bond acceptors are the CO groups of residues on the other chains. The OH group of hydroxyproline also participates in hydrogen bonding. The rise of the collagen helix is 2.9 Å (0.29 nm) per residue. See also : tertiary structure -- α helix -- β sheet
- La hélice de colágeno es un tipo de estructura secundaria de las proteínas que solamente la presenta el colágeno, que está formado por unas unidades denominadas tropocolágeno, y son estas las que presentan la hélice colágena.
- コラーゲンヘリックス(collagen helix)とは、コラーゲン中に良く現れるタンパク質の二次構造の一つである。グリシン-プロリン-ヒドロキシプロリンの3アミノ酸配列の繰り返しからなる三本鎖らせんから構成されている。三本の鎖は、プロリンとヒドロキシプロリンのピロリドン環由来の立体障害により安定化されている。ポリペプチド鎖がこのらせん構造を取ると、ピロリドン環は鎖間を広げ、αヘリックスよりも開いた構造を保つ。3本の鎖は水素結合により繋がっているが、水素原子の供給源はグリシンのアミノ基であり、受容源は他の鎖の残基のカルボキシル基である。ヒドロキシプロリンのカルボキシル基も水素結合に関与している。
|
| dbpprop:hasPhotoCollection
| |
| rdf:type
| |
| rdfs:comment
|
- In collagen, the collagen helix, or type 2 helix, is a major shape in secondary structure. It consists of a triple helix made of the repetitious amino acid sequence glycine - proline - hydroxyproline. Each of the three chains is stabilized by the steric repulsion due to the pyrrolidone rings of proline and hydroxyproline residues.
- La hélice de colágeno es un tipo de estructura secundaria de las proteínas que solamente la presenta el colágeno, que está formado por unas unidades denominadas tropocolágeno, y son estas las que presentan la hélice colágena.
|
| rdfs:label
|
- Collagen helix
- Hélice de colágeno
- コラーゲンヘリックス
|
| owl:sameAs
| |
| skos:subject
| |
| foaf:depiction
| |
| foaf:page
| |
| is owl:sameAs
of | |