CGS-21680 is a specific adenosine A2A subtype receptor agonist. It is usually presented as an organic hydrochloride salt with a molecular weight of 536.0 g/M. It is soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin. The chemical is currently used by researchers interested in studying neuronal transmission with a high-affinity, subtype specific analogue for adenosine.
| Property | Value |
| dbpedia-owl:abstract
|
- CGS-21680 is a specific adenosine A2A subtype receptor agonist. It is usually presented as an organic hydrochloride salt with a molecular weight of 536.0 g/M. It is soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin. The chemical is currently used by researchers interested in studying neuronal transmission with a high-affinity, subtype specific analogue for adenosine. This includes research in respiration where it is believed that A2A receptors are involved in rhythm generation in the pre-Bötzinger complex. The drug is not currently approved for use in a therapeutic capacity. It is currently manufactured by Tocris with the exclusive permission of Novartis Pharma AG, U.S. Patent 4,968,697. File:FlattenedRoundPills. jpg This pharmacology-related article is a stub. You can help Wikipedia by expanding it. v • d • e
|
| dbpedia-owl:iupacName
|
- 3-[4-[2-[6-amino-9-(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-ylpurin-2-ylamino]ethyl]phenyl]propanoic acid
|
| dbpedia-owl:thumbnail
| |
| dbpedia-owl:wikiPageExternalLink
| |
| dbpprop:imagefile
| |
| dbpprop:imagesize
| |
| dbpprop:iupacname
| |
| dbpprop:othernames
| |
| dbpprop:verifiedrevid
| |
| dbpprop:wikiPageUsesTemplate
| |
| dcterms:subject
| |
| rdf:type
| |
| rdfs:comment
|
- CGS-21680 is a specific adenosine A2A subtype receptor agonist. It is usually presented as an organic hydrochloride salt with a molecular weight of 536.0 g/M. It is soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin. The chemical is currently used by researchers interested in studying neuronal transmission with a high-affinity, subtype specific analogue for adenosine.
|
| rdfs:label
| |
| owl:sameAs
| |
| foaf:depiction
| |
| foaf:page
| |
| is dbpedia-owl:wikiPageRedirects
of | |
| is owl:sameAs
of | |
| is foaf:primaryTopic
of | |