Athymhormic syndrome, or psychic akinesia, is a rare neurological syndrome characterized by extreme passivity, apathy, blunted affect, and a profound generalized loss of self-motivation and conscious thought. For example, a patient with this syndrome might sustain severe burns on contact with a hot stove, due to lacking the will to move away despite experiencing severe pain. The existence of such symptoms in patients after damage to certain structures in the brain has been used in support of a physical model of motivation in human beings, wherein the limbic loop of the basal ganglia is the initiator of directed action and thought.

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  • Athymhormic syndrome, or psychic akinesia, is a rare neurological syndrome characterized by extreme passivity, apathy, blunted affect, and a profound generalized loss of self-motivation and conscious thought. For example, a patient with this syndrome might sustain severe burns on contact with a hot stove, due to lacking the will to move away despite experiencing severe pain. The existence of such symptoms in patients after damage to certain structures in the brain has been used in support of a physical model of motivation in human beings, wherein the limbic loop of the basal ganglia is the initiator of directed action and thought. The word Athymhormic is derived from the Greek (Greek: Thumos), which means mood or affect, and (Greek: Horme), which means impulse, drive, or appetite. First described by French neurologist Dominique Laplane in 1982 as ""PAP syndrome" (French: perte d'auto-activation psychique, or "loss of psychic autoactivation"), the syndrome is believed to be due to damage to areas of the basal ganglia or frontal cortex, specifically the striatum and globus pallidus, responsible for motivation and executive functions. It may occur without any preexisting psychiatric condition. (en)
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http://purl.org/linguistics/gold/hypernym
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  • Athymhormic syndrome, or psychic akinesia, is a rare neurological syndrome characterized by extreme passivity, apathy, blunted affect, and a profound generalized loss of self-motivation and conscious thought. For example, a patient with this syndrome might sustain severe burns on contact with a hot stove, due to lacking the will to move away despite experiencing severe pain. The existence of such symptoms in patients after damage to certain structures in the brain has been used in support of a physical model of motivation in human beings, wherein the limbic loop of the basal ganglia is the initiator of directed action and thought. (en)
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  • Athymhormic syndrome (en)
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