Caspar Röist (13 July 1478 – 6 May 1527) was a Swiss papal official and commander of the papacy's Swiss Guard. He died whilst commanding it in its last stand during the sack of Rome in 1527. A native of Zürich, and son of mayor of Zürich and colonel of the Swiss Guard Marx Röist (1454–1524), Röist was a student in Basel in 1494, and is recorded as a judge in Zürich during 1500–1505.He married Anna Meyer of Knonau in 1500, and later Elisabeth Klingler, likely in 1517.He served in the papal guard in the rank of a captain as a deputy in the absence of his father during 1518–1524, and after the death of his father as commander from August 1524 until his death.