About: Tetracycline-controlled transcriptional activation   Goto Sponge  NotDistinct  Permalink

An Entity of Type : yago:YagoPermanentlyLocatedEntity, within Data Space : dbpedia.org associated with source document(s)

Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of its derivatives (e.g. doxycycline). Tetracycline-controlled gene expression is based upon the mechanism of resistance to tetracycline antibiotic treatment found in gram-negative bacteria. In nature, the Ptet promoter expresses TetR, the repressor, and TetA, the protein that pumps tetracycline antibiotic out of the cell.

AttributesValues
rdf:type
rdfs:label
  • Tetracycline-controlled transcriptional activation
  • Attivazione trascrizionale controllata da tetraciclina
  • Régulation par la tétracycline
rdfs:comment
  • La régulation par la tétracycline est une méthode d'expression génique inductible dans laquelle la transcription est activée ou désactivée de manière réversible en présence de l'antibiotique tétracycline ou l'un de ses dérivés (doxycycline).
  • L'attivazione trascrizionale controllata da tetraciclina è un sistema di espressione genica inducibile nella quale la trascrizione è attivata o disattivata in modo reversibile in presenza dell'antibiotico tetraciclina, o di uno dei suoi derivati (ad esempio doxiciclina). In natura, il promotore Ptet esprime il fattore TetR, il repressore, e il fattore TetA, costituito da una proteina in grado di pompare all'esterno della cellula l'antibiotico tetraciclina. Il sistema viene distinto in Tet-On o Tet-Off a seconda che l'attivazione trascrizionale del gene di interesse sia rispettivamente indotta o repressa dalla presenza di tetraciclina.
  • Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of its derivatives (e.g. doxycycline). Tetracycline-controlled gene expression is based upon the mechanism of resistance to tetracycline antibiotic treatment found in gram-negative bacteria. In nature, the Ptet promoter expresses TetR, the repressor, and TetA, the protein that pumps tetracycline antibiotic out of the cell.
sameAs
dct:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
Link from a Wikipage to an external page
foaf:depiction
  • External Image
foaf:isPrimaryTopicOf
thumbnail
prov:wasDerivedFrom
has abstract
  • Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of its derivatives (e.g. doxycycline). Tetracycline-controlled gene expression is based upon the mechanism of resistance to tetracycline antibiotic treatment found in gram-negative bacteria. In nature, the Ptet promoter expresses TetR, the repressor, and TetA, the protein that pumps tetracycline antibiotic out of the cell. The difference between Tet-On and Tet-Off is not whether the transactivator turns a gene on or off, as the name might suggest; rather, both proteins activate expression. The difference relates to their respective response to tetracycline or doxycycline (Dox, a more stable tetracycline analogue); Tet-Off activates expression in the absence of Dox, whereas Tet-On activates in the presence of Dox.
  • La régulation par la tétracycline est une méthode d'expression génique inductible dans laquelle la transcription est activée ou désactivée de manière réversible en présence de l'antibiotique tétracycline ou l'un de ses dérivés (doxycycline).
  • L'attivazione trascrizionale controllata da tetraciclina è un sistema di espressione genica inducibile nella quale la trascrizione è attivata o disattivata in modo reversibile in presenza dell'antibiotico tetraciclina, o di uno dei suoi derivati (ad esempio doxiciclina). In natura, il promotore Ptet esprime il fattore TetR, il repressore, e il fattore TetA, costituito da una proteina in grado di pompare all'esterno della cellula l'antibiotico tetraciclina. Il sistema viene distinto in Tet-On o Tet-Off a seconda che l'attivazione trascrizionale del gene di interesse sia rispettivamente indotta o repressa dalla presenza di tetraciclina.
http://purl.org/voc/vrank#hasRank
http://purl.org/li...ics/gold/hypernym
is Link from a Wikipage to another Wikipage of
is Wikipage redirect of
is foaf:primaryTopic of
Faceted Search & Find service v1.17_git21 as of Mar 09 2019


Alternative Linked Data Documents: PivotViewer | iSPARQL | ODE     Content Formats:       RDF       ODATA       Microdata      About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3230 as of May 1 2019, on Linux (x86_64-generic-linux-glibc25), Single-Server Edition (61 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2019 OpenLink Software