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Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle. Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria.

AttributesValues
rdf:type
rdfs:label
  • Spectinomycin
  • Espectinomicina
  • Spectinomycin
  • Spectinomicina
  • Spectinomycine
  • スペクチノマイシン
  • Espectinomicina
rdfs:comment
  • Spectinomycin ist ein Aminoglycosid-Antibiotikum aus Streptomyceten (Streptomyces spectabilis).
  • La espectinomicina es un antibiótico bacteriostático derivado de la familia de los aminoglicósidos descubierto en 1962 a partir de una cepa de Streptomyces spectabilis. Su estructura molecular se basa en un anillo de aminociclitol. No es nefrotóxico ni ototóxico.
  • La spectinomycine est une molécule antibiotique, c'est un aminoside.
  • La spectinomicina è un antibiotico inibitore della sintesi proteica prodotto dal batterio Streptomyces spectabilis. Molecola di ricerca Upjohn poi acquista da Pfizer, che la commercializza come Trobicin.
  • スペクチノマイシン(Spectinomycin)とは真正細菌のStreptomyces spectabilis によって産生されるアミノグリコシド系抗生物質であり、淋菌感染症の治療に用いられる。塩酸塩がトロビシン(商品名)として商品化されている。臀部筋肉内注射で用いられる。 WHO必須医薬品モデル・リストに収載されている。 スペクチノマイシンは1961年に発見された。日本では1978年5月に承認された。米国ではトロビシンは2001年に供給が中止された。
  • Espectinomicina (nome comercial: Trobicim) é um antibiótico bacteriostático da família dos aminoglicosídeos. Atua inibindo a síntese de proteínas. Sua principal indicação é contra gonococos, como uma alternativa aos antibióticos de primeira escolha: betalactâmicos e quinolonas. Administrado por via intramuscular, em 40 mg/kg dose única. Está sendo substituído pelas novas cefalosporinas.
  • Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle. Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria.
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  • Spectinomycin ist ein Aminoglycosid-Antibiotikum aus Streptomyceten (Streptomyces spectabilis).
  • La espectinomicina es un antibiótico bacteriostático derivado de la familia de los aminoglicósidos descubierto en 1962 a partir de una cepa de Streptomyces spectabilis. Su estructura molecular se basa en un anillo de aminociclitol. No es nefrotóxico ni ototóxico.
  • La spectinomycine est une molécule antibiotique, c'est un aminoside.
  • La spectinomicina è un antibiotico inibitore della sintesi proteica prodotto dal batterio Streptomyces spectabilis. Molecola di ricerca Upjohn poi acquista da Pfizer, che la commercializza come Trobicin.
  • Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle. Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria. Spectinomycin was discovered 1961. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost in the developing world is about US$5 per dose. It is not available in the United States. It is made from the bacterium Streptomyces spectabilis.
  • スペクチノマイシン(Spectinomycin)とは真正細菌のStreptomyces spectabilis によって産生されるアミノグリコシド系抗生物質であり、淋菌感染症の治療に用いられる。塩酸塩がトロビシン(商品名)として商品化されている。臀部筋肉内注射で用いられる。 WHO必須医薬品モデル・リストに収載されている。 スペクチノマイシンは1961年に発見された。日本では1978年5月に承認された。米国ではトロビシンは2001年に供給が中止された。
  • Espectinomicina (nome comercial: Trobicim) é um antibiótico bacteriostático da família dos aminoglicosídeos. Atua inibindo a síntese de proteínas. Sua principal indicação é contra gonococos, como uma alternativa aos antibióticos de primeira escolha: betalactâmicos e quinolonas. Administrado por via intramuscular, em 40 mg/kg dose única. Está sendo substituído pelas novas cefalosporinas.
ATC prefix
  • J01
ATC suffix
  • XX04
CAS number
  • 1695-77-8
ChEBI
  • 9215
DrugBank
  • DB00919
FDA UNII code
  • 93AKI1U6QF
IUPAC name
  • (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one
PubChem
  • 15541
c
ChEMBL
ChemSpiderID
H
KEGG
  • D08526
legal status
  • not available in US
molecular weight
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