Research in Computational Molecular Biology (RECOMB) is an annual academic conference on the subjects of bioinformatics and computational biology. The conference has been held every year since 1997 and is a major international conference in computational biology, alongside the ISMB and ECCB conferences. The conference is affiliated with the International Society for Computational Biology. Since the first conference, authors of accepted proceedings papers have been invited to submit a revised version to a special issue of the Journal of Computational Biology.