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Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, the development of which was discontinued in 2007. The drug has shown to have a similar spectrum of activity to voriconazole, with an increased half-life. However, ravuconazole has limited activity against species of Fusarium, Scedosporium, and Zygomycetes.

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  • Ravuconazole (en)
  • Ravuconazol (pt)
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  • Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, the development of which was discontinued in 2007. The drug has shown to have a similar spectrum of activity to voriconazole, with an increased half-life. However, ravuconazole has limited activity against species of Fusarium, Scedosporium, and Zygomycetes. (en)
  • Ravuconazol é um fármaco antifúngico triazólico desenvolvido pela Bristol-Myers Squibb, que está em fase de testes clínicos. A droga tem demonstrado um espectro de ação similar ao voriconazol, com uma meia-vida biológica aumentada. Entretanto, o ravuconazol tem uma limitada ação contra espécies dos gêneros Fusarium, e Zygomycetes. O ravuconazol possui atividade anti-Trypanosoma in vivo e in vitro, e devido a meia-vida plasmática elevada (4 a 8 dias) em humanos faz dele uma droga promissora para ser usada no tratamento da doença de Chagas. (pt)
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  • C[C@@H][C@]c1ccccc1F (en)
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  • OPAHEYNNJWPQPX-RCDICMHDSA-N (en)
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