A liver sinusoid is a type of capillary known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a fenestrated capillary, having discontinuous endothelium that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein. The Kupffer cells can take up and destroy foreign material such as bacteria. Hepatocytes are separated from the sinusoids by the space of Disse. Hepatic stellate cells are present in the space of Disse and are involved in scar formation in response to liver damage.
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| - أشباه الجيوب الكبدية (ar)
- Lebersinusoid (de)
- Sinusoïdes hépatiques (fr)
- Sinusoidi epatici (it)
- Liver sinusoid (en)
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| - أشباه الجيوب الكبدية (بالإنجليزية: liver sinusoids) هي نوع من (مع بطانة متقطعة منوفذة)، والتي تعتبر كموقع لتجمع الدم الغني بالأكسجين القادم من الشريان الكبدي والدم الغني بالغذاء القادم من وريد الباب. الخلية الكبدية تنفصل من الجيوب بواسطة . توجد خلايا كوبفر في داخل الجيوب، وتستطيع التقاط وتحطيم المواد الغريبة مثل البكتيريا. (ar)
- Ein Lebersinusoid (Vena intralobularis) ist ein erweitertes Kapillargefäß (Sinusoid), das das sauerstoffreiche Blut aus der Leberarterie (Arteria hepatica propria) und das nährstoffreiche Blut aus der Pfortader (Vena portae) transportiert. Die Sinusoide verfügen über Kupffer-Zellen, welche Fremdstoffe (beispielsweise Bakterien) aufnehmen und zerstören können. Schädigungen des Epithels der Lebersinusoide kann zur Venösen okklusiven Leberkrankheit führen. (de)
- Les sinusoïdes hépatiques sont des capillaires sinusoïdes situées au niveau des organes hématopoïétique. (fr)
- I sinusoidi epatici sono capillari sanguiferi, a parete sottile, lume ampio e irregolare ed endotelio fenestrato e tortuoso, situati nel fegato. (it)
- A liver sinusoid is a type of capillary known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a fenestrated capillary, having discontinuous endothelium that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein. The Kupffer cells can take up and destroy foreign material such as bacteria. Hepatocytes are separated from the sinusoids by the space of Disse. Hepatic stellate cells are present in the space of Disse and are involved in scar formation in response to liver damage. (en)
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| - Basic liver structure (en)
- Sinusoid of a rat liver with fenestrated endothelial cells. Fenestrae are approx 100 nm diameter, and the sinusoidal width 5 µm. (en)
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| - Hepatic structure2.svg (en)
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| - أشباه الجيوب الكبدية (بالإنجليزية: liver sinusoids) هي نوع من (مع بطانة متقطعة منوفذة)، والتي تعتبر كموقع لتجمع الدم الغني بالأكسجين القادم من الشريان الكبدي والدم الغني بالغذاء القادم من وريد الباب. الخلية الكبدية تنفصل من الجيوب بواسطة . توجد خلايا كوبفر في داخل الجيوب، وتستطيع التقاط وتحطيم المواد الغريبة مثل البكتيريا. (ar)
- Ein Lebersinusoid (Vena intralobularis) ist ein erweitertes Kapillargefäß (Sinusoid), das das sauerstoffreiche Blut aus der Leberarterie (Arteria hepatica propria) und das nährstoffreiche Blut aus der Pfortader (Vena portae) transportiert. Die Sinusoide verfügen über Kupffer-Zellen, welche Fremdstoffe (beispielsweise Bakterien) aufnehmen und zerstören können. Schädigungen des Epithels der Lebersinusoide kann zur Venösen okklusiven Leberkrankheit führen. (de)
- Les sinusoïdes hépatiques sont des capillaires sinusoïdes situées au niveau des organes hématopoïétique. (fr)
- A liver sinusoid is a type of capillary known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a fenestrated capillary, having discontinuous endothelium that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein. The liver sinusoid has a larger caliber than other types of capillaries and has a lining of specialised endothelial cells known as the liver sinusoidal endothelial cells (LSECs), and Kupffer cells. The cells are porous and have a scavenging function. The LSECs make up around half of the non-parenchymal cells in the liver and are flattened and fenestrated. LSECs have many fenestrae that gives easy communication between the sinusoidal lumen and the space of Disse. They play a part in filtration, endocytosis, and in the regulation of blood flow in the sinusoids. The Kupffer cells can take up and destroy foreign material such as bacteria. Hepatocytes are separated from the sinusoids by the space of Disse. Hepatic stellate cells are present in the space of Disse and are involved in scar formation in response to liver damage. Defenestration also known as capillarisation happens when LSECs are lost rendering the sinusoid as an ordinary capillary. This process precedes fibrosis. (en)
- I sinusoidi epatici sono capillari sanguiferi, a parete sottile, lume ampio e irregolare ed endotelio fenestrato e tortuoso, situati nel fegato. (it)
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