General Lester L. Lyles (born April 20, 1946) is a former United States Air Force general, Vice Chief of Staff of the United States Air Force, and Commander, Air Force Materiel Command, Wright-Patterson Air Force Base, Ohio. After retirement from the Air Force in 2003, he became a company director for General Dynamics, DPL Inc., KBR, Inc., Precision Castparts Corp., , Battelle Memorial Institute and USAA. Lyles is also a trustee of Analytic Services and a managing partner of Four Seasons Ventures, LLC.