Leona Valley AVA is an American Viticulture Area (AVA) in northeastern Los Angeles County, California. It is located in Leona Valley within the Sierra Pelona Mountains of Southern California. The 13.4-square-mile (35 km2) Leona Valley American Viticulture Area was established on October 29, 2008 by the Alcohol and Tobacco Tax and Trade Bureau, announced by the publication of Treasury Decision TTB-71.