Isa Mammetgulyyev (born 8 January 1997) is a Turkmen tennis player. Mammetgulyyev has a career high ATP singles ranking of 1115 achieved on 25 July 2016. He also has a career high ATP doubles ranking of 1189, achieved on 19 September 2016. Mammetgulyyev has represented Turkmenistan at Davis Cup, where he has a win–loss record of 18–11. He played at the 2014 Asian Games on Mixed doubles with Anastasiýa Prenko and Men's team event.