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Glyceryl behenate is a fat used in cosmetics, foods, and oral pharmaceutical formulations. In cosmetics, it is mainly used as a viscosity-increasing agent in emulsions. In pharmaceutical formulations, glyceryl behenate is mainly used as a tablet and capsule lubricant and as a lipidic coating excipient. It has been investigated for the encapsulation of various drugs such as retinoids. It has also been investigated for use in the preparation of sustained release tablets as a matrix-forming agent for the controlled release of water-soluble drugs and as a lubricant in oral solid dosage formulations. It can also be used as a hot-melt coating agent sprayed onto a powder.

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  • Glyceryl behenate (en)
  • ベヘン酸グリセリル (ja)
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  • ベヘン酸グリセリル(Glyceryl behenate)は、化粧品、食品、口腔医薬製剤等に用いられる脂肪である。化粧品では、主にエマルションに対する増粘剤として用いられる。医薬製剤に用いる場合は、主に錠剤やカプセル剤の潤滑剤や脂質被覆賦形剤として用いられる。レチノイド等の様々な薬剤をカプセル化する目的やマトリックス形成による薬剤へのの付与、粉薬にスプレーされる熱溶解被覆剤としても研究されている。 顔の皮膚の皮脂腺を詰まらせないため、ニキビのできにくい化粧品材料として広く用いられている。 また、固体脂質ナノ粒子や等の脂質ナノ粒子の合成にも広く用いられている。化学的には、ベヘン酸グリセリルは、ベヘン酸とグリセリン(脂質)の様々なエステルの混合物であるが、その大部分は、2分子のベヘン酸を含むである。 (ja)
  • Glyceryl behenate is a fat used in cosmetics, foods, and oral pharmaceutical formulations. In cosmetics, it is mainly used as a viscosity-increasing agent in emulsions. In pharmaceutical formulations, glyceryl behenate is mainly used as a tablet and capsule lubricant and as a lipidic coating excipient. It has been investigated for the encapsulation of various drugs such as retinoids. It has also been investigated for use in the preparation of sustained release tablets as a matrix-forming agent for the controlled release of water-soluble drugs and as a lubricant in oral solid dosage formulations. It can also be used as a hot-melt coating agent sprayed onto a powder. (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Glyceryl_behenate.svg
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  • Glyceryl behenate.svg (en)
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  • Glycerol behenate; Glycerin behenate; Glycerol docosanoate (en)
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  • Glyceryl behenate is a fat used in cosmetics, foods, and oral pharmaceutical formulations. In cosmetics, it is mainly used as a viscosity-increasing agent in emulsions. In pharmaceutical formulations, glyceryl behenate is mainly used as a tablet and capsule lubricant and as a lipidic coating excipient. It has been investigated for the encapsulation of various drugs such as retinoids. It has also been investigated for use in the preparation of sustained release tablets as a matrix-forming agent for the controlled release of water-soluble drugs and as a lubricant in oral solid dosage formulations. It can also be used as a hot-melt coating agent sprayed onto a powder. It is used widely in cosmetics as non-comedogenic (non- pimple causing substance) ingredient. It does not clog the oil pores of facial skin. It is also used widely as ingredient for preparation of lipidic nano-particles such as solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC). Chemically, glyceryl behenate is a mixture of various esters of behenic acid and glycerol (glycerides). The mixture predominantly contains the diester glyceryl dibehenate. (en)
  • ベヘン酸グリセリル(Glyceryl behenate)は、化粧品、食品、口腔医薬製剤等に用いられる脂肪である。化粧品では、主にエマルションに対する増粘剤として用いられる。医薬製剤に用いる場合は、主に錠剤やカプセル剤の潤滑剤や脂質被覆賦形剤として用いられる。レチノイド等の様々な薬剤をカプセル化する目的やマトリックス形成による薬剤へのの付与、粉薬にスプレーされる熱溶解被覆剤としても研究されている。 顔の皮膚の皮脂腺を詰まらせないため、ニキビのできにくい化粧品材料として広く用いられている。 また、固体脂質ナノ粒子や等の脂質ナノ粒子の合成にも広く用いられている。化学的には、ベヘン酸グリセリルは、ベヘン酸とグリセリン(脂質)の様々なエステルの混合物であるが、その大部分は、2分子のベヘン酸を含むである。 (ja)
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  • Glycerol behenate; Glycerin behenate; Glycerol docosanoate (en)
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