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Glomerulation refers to bladder hemorrhages which are thought to be associated with some types of interstitial cystitis (IC). The presence of glomerulations, also known as petechial hemorrhages, in the bladder suggests that the bladder wall has been damaged, irritated, and/or inflamed. Petechial hemorrhages originate from punctuate hemorrhages. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Diagnostic Criteria for IC, developed in 1987, required the presence of glomerulations or Hunner's Ulcers for diagnosis of IC and is still used today, to determine eligibility for some clinical trials. However other research has theorized that the hydrodistention procedure used for the diagnosis of IC itself may have created these tiny broken blood vessels. Studies have fou

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  • Glomerulation (en)
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  • Glomerulation refers to bladder hemorrhages which are thought to be associated with some types of interstitial cystitis (IC). The presence of glomerulations, also known as petechial hemorrhages, in the bladder suggests that the bladder wall has been damaged, irritated, and/or inflamed. Petechial hemorrhages originate from punctuate hemorrhages. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Diagnostic Criteria for IC, developed in 1987, required the presence of glomerulations or Hunner's Ulcers for diagnosis of IC and is still used today, to determine eligibility for some clinical trials. However other research has theorized that the hydrodistention procedure used for the diagnosis of IC itself may have created these tiny broken blood vessels. Studies have fou (en)
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  • Glomerulation refers to bladder hemorrhages which are thought to be associated with some types of interstitial cystitis (IC). The presence of glomerulations, also known as petechial hemorrhages, in the bladder suggests that the bladder wall has been damaged, irritated, and/or inflamed. Petechial hemorrhages originate from punctuate hemorrhages. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Diagnostic Criteria for IC, developed in 1987, required the presence of glomerulations or Hunner's Ulcers for diagnosis of IC and is still used today, to determine eligibility for some clinical trials. However other research has theorized that the hydrodistention procedure used for the diagnosis of IC itself may have created these tiny broken blood vessels. Studies have found glomerulations in asymptomatic populations, suggesting that they are not applicable as a marker for IC. Thus, a diagnosis of IC is now based upon other, less invasive methods, such as the PUF Scale (Pelvic Pain and Urgency/Frequency Patient Symptom Scale). Glomerulation has been observed to be one of the feature for prostate cancer. However, efforts to determine whether this is association or causation have concluded that while glomerulations may be a common finding in individuals with prostate cancer, they are not a significant predictor. (en)
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