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GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates many genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-forming stem cells. GATA2 is encoded by the GATA2 gene, a gene which often suffers germline and somatic mutations which lead to a wide range of familial and sporadic diseases, respectively. The gene and its product are targets for the treatment of these diseases.

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  • GATA2 (es)
  • GATA2 (en)
  • GATA2 (fr)
  • GATA2 (uk)
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  • Le GATA2 est une protéine appartenant à la famille des facteurs de transcription de type GATA dont le gène est le GATA2 situé sur le chromosome 3 humain. (fr)
  • GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. It regulates many genes that are critical for the embryonic development, self-renewal, maintenance, and functionality of blood-forming, lympathic system-forming, and other tissue-forming stem cells. GATA2 is encoded by the GATA2 gene, a gene which often suffers germline and somatic mutations which lead to a wide range of familial and sporadic diseases, respectively. The gene and its product are targets for the treatment of these diseases. (en)
  • GATA2 o factor de unión a GATA 2 es un factor de transcripción , es decir, una proteína nuclear que regula la expresión de genes .​ Regula muchos genes que son críticos para el desarrollo embrionario , la autorrenovación , el mantenimiento y la funcionalidad de lascélulas madre formadoras de sangre , formadoras de sistemas linfáticos y otras células madre formadoras de tejidos. GATA2 está codificado por el gen GATA2, un gen que a menudo sufre de línea germinal y somático mutaciones que conducen a una amplia gama de enfermedades familiares y esporádicas, respectivamente. El gen y su producto son objetivos para el tratamiento de estas enfermedades.​ ​Las mutaciones inactivadoras del gen GATA2 provocan una reducción en los niveles celulares de GATA2 y el desarrollo de una amplia gama de trast (es)
  • GATA2 (англ. GATA binding protein 2) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 3-ї хромосоми. Довжина поліпептидного ланцюга білка становить 480 амінокислот, а молекулярна маса — 50 500. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk)
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