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Fosphenytoin (fosphenytoin sodium, trade names Cerebyx, Parke-Davis; Prodilantin, Pfizer Holding France) is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is most commonly used in the acute treatment convulsive status epilepticus. Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin.

AttributesValues
rdf:type
rdfs:label
  • Fosphenytoin
rdfs:comment
  • Fosphenytoin (fosphenytoin sodium, trade names Cerebyx, Parke-Davis; Prodilantin, Pfizer Holding France) is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is most commonly used in the acute treatment convulsive status epilepticus. Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin.
sameAs
dct:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
foaf:depiction
  • External Image
foaf:isPrimaryTopicOf
thumbnail
prov:wasDerivedFrom
has abstract
  • Fosphenytoin (fosphenytoin sodium, trade names Cerebyx, Parke-Davis; Prodilantin, Pfizer Holding France) is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is most commonly used in the acute treatment convulsive status epilepticus. Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin.
ATC prefix
  • N03
ATC suffix
  • AB05
Bioavailability
CAS number
  • 93390-81-9
DrugBank
  • DB01320
FDA UNII code
  • B4SF212641
IUPAC name
  • (2,5-Dioxo-4,4-diphenyl-imidazolidin-1-yl)methoxyphosphonic acid
PubChem
  • 56339
c
ChEMBL
ChemSpiderID
elimination half-life
  • 900.0
excretion
H
image
  • Fosphenytoin 3D ball.png
IUPHAR ligand
KEGG
  • D07993
legal status
  • Rx-only
MedlinePlus
  • a604036
metabolism
molecular weight
n
O
p
pregnancy US
  • D
protein bound
routes of administration
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