David Lawrence Gregg (July 21, 1819 – December 23, 1868) was an American politician from Pennsylvania. He rose to prominence in Illinois politics, first in the Illinois House of Representatives, then as United States Attorney, and Illinois Secretary of State. In 1853, Franklin Pierce appointed Gregg the Commissioner to the Kingdom of Hawaii to negotiate its annexation at the request of its king, Kamehameha III. In response, he cited the U.S. Constitution as not allowing annexation of a foreign state. (Texas had, in fact, been annexed a few years before with dubious legality.) His later years were spent in Carson City, Nevada.