About: Cryogenine

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Cryogenine, also known as vertine or (10α)-4,5-dimethoxy-2-hydroxylythran-12-one, is a biphenylquinolizidine lactone alkaloid from the plants Sinicuichi (Heimia salicifolia) and . The compound has no psychoactive properties in humans up to 310 mg, but has shown anti-inflammatory activity similar to aspirin. The freebase form melts at 250–251 °C and is soluble in moderately polar organic solvents such as chloroform, methylene chloride, benzene, and methanol, but is insoluble in water and petroleum ether.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:Abstraction100002137 yago:AliphaticCompound114601294 yago:Alkaloid114712692 yago:Alkene114713120 yago:Chemical114806838 yago:Compound114818238 yago:Element114840755 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Quintessence114847103 yago:Relation100031921 chemical compound drug yago:Substance100019613 yago:WikicatAlkaloids yago:WikicatAlkenes yago:WikicatPhenolEthers umbel-rc:DrugProduct
rdfs:label	Criogenina (es) Cryogenine (en)
rdfs:comment	Cryogenine, also known as vertine or (10α)-4,5-dimethoxy-2-hydroxylythran-12-one, is a biphenylquinolizidine lactone alkaloid from the plants Sinicuichi (Heimia salicifolia) and . The compound has no psychoactive properties in humans up to 310 mg, but has shown anti-inflammatory activity similar to aspirin. The freebase form melts at 250–251 °C and is soluble in moderately polar organic solvents such as chloroform, methylene chloride, benzene, and methanol, but is insoluble in water and petroleum ether. (en) La criogenina, también conocida como vertina o (10α)-4,5-dimetoxi-2-hidroxilitran-12-ona, es un alcaloide bifenilquinolizidina lactona que se encuentra en las plantas y . El compuesto no tiene propiedades psicoactivas en los seres humanos hasta dosis de 310 mg, pero ha demostrado una actividad antiinflamatoria similar a la aspirina. La base libre se funde a 250-251 Cº y es soluble en disolventes orgánicos moderadamente polares tales como el cloroformo, cloruro de metileno, benceno y metanol , pero es insoluble en agua y éter de petróleo. (es)
foaf:depiction
dcterms:subject	Alkaloids Alkene derivatives Lactones Catechol ethers
Wikipage page ID	1327211 (xsd:integer)
Wikipage revision ID	966144853 (xsd:integer)
Link from a Wikipage to another Wikipage	Psychoactive drug dbr:Benzene Alkaloid Anti-inflammatory Petroleum ether Alkaloids Alkene derivatives Lactones Thin layer chromatography Lactone Heimia Heimia salicifolia Catechol ethers Aspirin Chloroform Methylene chloride dbr:Methanol Solvent Freebase (chemistry) List of entheogens P-nitroaniline dbr:Heimia_myrtifolia dbr:Sinicuichine
sameAs	Cryogenine Cryogenine Cryogenine Cryogenine Cryogenine Cryogenine Cryogenine Cryogenine
dbp:wikiPageUsesTemplate	dbt:About dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Ebicite dbt:Fdacite dbt:Stdinchicite
thumbnail	wiki-commons:Special:FilePath/Cryogenine.svg?width=300
ATC prefix	none (en)
c	26 (xsd:integer)
CAS number	10308 (xsd:integer)
ChEMBL	1173218 (xsd:integer)
ChemSpiderID	4474587 (xsd:integer)
H	29 (xsd:integer)
IUPAC name	-45 (xsd:integer)
n	1 (xsd:integer)
O	5 (xsd:integer)
PubChem	5315204 (xsd:integer)
SMILES	O=C/4O[C@H]5C[C@@H]1N[C@H]C5 (en)
StdInChI	1 (xsd:integer)
StdInChIKey	WCZWUYYJZVBKDZ-VMSBZHFZSA-N (en)
UNII	OR77C8W8TA (en)
Verifiedfields	changed (en)
verifiedrevid	460108663 (xsd:integer)
width	200 (xsd:integer)
has abstract	Cryogenine, also known as vertine or (10α)-4,5-dimethoxy-2-hydroxylythran-12-one, is a biphenylquinolizidine lactone alkaloid from the plants Sinicuichi (Heimia salicifolia) and . The compound has no psychoactive properties in humans up to 310 mg, but has shown anti-inflammatory activity similar to aspirin. The freebase form melts at 250–251 °C and is soluble in moderately polar organic solvents such as chloroform, methylene chloride, benzene, and methanol, but is insoluble in water and petroleum ether. In the development of thin layer chromatography plates with diazotized p-nitroaniline spray, cryogenine produces a purple spot (as does , another biphenylquinolizidine lactone alkaloid found in Heimia species). (en) La criogenina, también conocida como vertina o (10α)-4,5-dimetoxi-2-hidroxilitran-12-ona, es un alcaloide bifenilquinolizidina lactona que se encuentra en las plantas y . El compuesto no tiene propiedades psicoactivas en los seres humanos hasta dosis de 310 mg, pero ha demostrado una actividad antiinflamatoria similar a la aspirina. La base libre se funde a 250-251 Cº y es soluble en disolventes orgánicos moderadamente polares tales como el cloroformo, cloruro de metileno, benceno y metanol , pero es insoluble en agua y éter de petróleo. En el revelado de placas de cromatografía de capa fina con una pulverización de p-nitroanilina diazotizada, la criogenina produce una mancha púrpura (como lo hace la , otro alcaloide bifenilquinolizidina lactona que se encuentra en las especies de Heimia). (es)
gold:hypernym	Alkaloid
prov:wasDerivedFrom	wikipedia-en:Cryogenine?oldid=966144853&ns=0
page length (characters) of wiki page	2958 (xsd:nonNegativeInteger)
CAS number	10308-13-1
ChEMBL	1173218

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