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About: Acivicin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Thinking105770926, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:WikicatAminoAcidDerivativesyago:WikicatMolecularFormulasyago:Abstraction100002137yago:Calculation105802185yago:Cognition100023271yago:Communication100033020yago:DerivedFunction106014730yago:Formula106816935yago:HigherCognitiveProcess105770664yago:Message106598915yago:MolecularFormula106817173yago:ProblemSolving105796750yago:Process105701363yago:PsychologicalFeature100023100chemical compounddrugyago:Statement106722453yago:Thinking105770926 New Facet based on Instances of this Class

Acivicin is an analog of glutamine. It is an inhibitor of gamma-glutamyl transferase. It is a fermentation product of . It interferes with glutamate metabolism and inhibits glutamate dependent synthesis of enzymes, and is thereby potentially helpful in treatment of solid tumors. After its discovery in 1972, acivicin was studied as an anti-cancer agent, but trials were unsuccessful due to toxicity.