The 2009–10 Louisville Cardinals men's basketball team represented the University of Louisville during the 2009–10 NCAA Division I men's basketball season, Louisville's 96th season of intercollegiate competition. The Cardinals competed in the Big East Conference and were coached by Rick Pitino, who was in his ninth season. The team played its home games on Denny Crum Court at Freedom Hall, the final season before moving to the KFC Yum! Center.