About: Promegestone     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Substance100019613, within Data Space : dbpedia.org associated with source document(s)

Promegestone (INN) (brand name Surgestone), also known as 17α,21-dimethyl-Δ9-19-norprogesterone or 17α,21-dimethyl-19-norpregna-4,9-diene-3,20-dione, is a steroidal progestin of the 19-norprogesterone group which was introduced in 1983 and is marketed in France, Portugal, and Argentina. Indications include gynaecological conditions caused by luteal insufficiency, including premenopausal disorders, dysmenorrhea, and premenstrual syndrome. Promegestone has weak glucocorticoid activity, but does not bind to the androgen receptor or possess antimineralocorticoid activity. In addition, promegestone has been found to act as a non-competitive antagonist of the nicotinic acetylcholine receptor, similarly to progesterone. The drug is mainly bound to albumin; it does not bind to sex hormone-binding

AttributesValues
rdf:type
rdfs:label
  • Promegestone
rdfs:comment
  • Promegestone (INN) (brand name Surgestone), also known as 17α,21-dimethyl-Δ9-19-norprogesterone or 17α,21-dimethyl-19-norpregna-4,9-diene-3,20-dione, is a steroidal progestin of the 19-norprogesterone group which was introduced in 1983 and is marketed in France, Portugal, and Argentina. Indications include gynaecological conditions caused by luteal insufficiency, including premenopausal disorders, dysmenorrhea, and premenstrual syndrome. Promegestone has weak glucocorticoid activity, but does not bind to the androgen receptor or possess antimineralocorticoid activity. In addition, promegestone has been found to act as a non-competitive antagonist of the nicotinic acetylcholine receptor, similarly to progesterone. The drug is mainly bound to albumin; it does not bind to sex hormone-binding
sameAs
dct:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
foaf:depiction
  • External Image
foaf:isPrimaryTopicOf
thumbnail
prov:wasDerivedFrom
has abstract
  • Promegestone (INN) (brand name Surgestone), also known as 17α,21-dimethyl-Δ9-19-norprogesterone or 17α,21-dimethyl-19-norpregna-4,9-diene-3,20-dione, is a steroidal progestin of the 19-norprogesterone group which was introduced in 1983 and is marketed in France, Portugal, and Argentina. Indications include gynaecological conditions caused by luteal insufficiency, including premenopausal disorders, dysmenorrhea, and premenstrual syndrome. Promegestone has weak glucocorticoid activity, but does not bind to the androgen receptor or possess antimineralocorticoid activity. In addition, promegestone has been found to act as a non-competitive antagonist of the nicotinic acetylcholine receptor, similarly to progesterone. The drug is mainly bound to albumin; it does not bind to sex hormone-binding globulin, and binds only weakly to transcortin.
ATC prefix
  • G03
ATC suffix
  • DB07
CAS number
  • 34184-77-5
IUPAC name
  • (8S,13S,14S,17S)-13,17-Dimethyl-17-propionyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
PubChem
  • 36709
c
ChemSpiderID
H
KEGG
  • D08431
molecular weight
O
smiles
  • CCC[C@]1C
StdInChI
StdInChIKey
  • QFFCYTLOTYIJMR-XMGTWHOFSA-N
synonyms
  • R-5020; RU-5020
http://purl.org/voc/vrank#hasRank
http://purl.org/li...ics/gold/hypernym
is Link from a Wikipage to another Wikipage of
Faceted Search & Find service v1.17_git39 as of Aug 09 2019


Alternative Linked Data Documents: PivotViewer | iSPARQL | ODE     Content Formats:       RDF       ODATA       Microdata      About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3235 as of Jun 25 2020, on Linux (x86_64-generic-linux-glibc25), Single-Server Edition (61 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2020 OpenLink Software