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About: Proglumide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Whole100003553, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substancePill (pharmacy)yago:WikicatCholecystokininAntagonistsyago:WikicatMolecularFormulasyago:Abstraction100002137yago:Adversary109773245yago:CausalAgent100007347yago:Communication100033020yago:Formula106816935yago:LivingThing100004258yago:Message106598915yago:MolecularFormula106817173yago:Object100002684yago:Organism100004475yago:Person100007846yago:PhysicalEntity100001930yago:YagoLegalActoryago:YagoLegalActorGeodrugyago:Statement106722453yago:Whole100003553 New Facet based on Instances of this Class

Proglumide (Milid) is a drug that inhibits gastrointestinal motility and reduces gastric secretions. It acts as a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. It was used mainly in the treatment of stomach ulcers, although it has now been largely replaced by newer drugs for this application. Proglumide has also been shown to act as a δ-opioid agonist, which may contribute to its analgesic effects.