The 2010 Louisiana–Lafayette Ragin' Cajuns football team represented the University of Louisiana at Lafayette in the 2010 NCAA Division I FBS college football season. The Ragin' Cajans were led by ninth-year head coach Rickey Bustle and played their home games at Cajun Field. The schedule featured a nationally-televised game from Cajun Field against Oklahoma State on October 8. In five home games the average attendance at Cajun Field was 17,383, with a season-high of 25,000 attending the Oklahoma State game.