The 1980 Stanford Cardinals football team represented Stanford University in the Pacific-10 Conference during the 1980 NCAA Division I-A football season. Following the surprise resignation of Rod Dowhower after one season in January, Stanford's new head coach was alumnus Paul Wiggin, and he led the Cardinals to a 6–5 record (3–4 in Pac-10, tied for sixth). Home games were played on campus at Stanford Stadium in Stanford, California.