@prefix foaf: .
@prefix wikipedia-en: .
@prefix dbr: .
wikipedia-en:Netarsudil foaf:primaryTopic dbr:Netarsudil .
@prefix dbo: .
dbr:Rho_kinase_inhibitor dbo:wikiPageWikiLink dbr:Netarsudil .
dbr:ATC_code_S01 dbo:wikiPageWikiLink dbr:Netarsudil .
@prefix rdf: .
@prefix owl: .
dbr:Netarsudil rdf:type owl:Thing .
@prefix ns6: .
dbr:Netarsudil rdf:type ns6:ChemicalObject ,
dbo:ChemicalSubstance .
@prefix wikidata: .
dbr:Netarsudil rdf:type wikidata:Q8386 ,
dbo:Drug ;
owl:sameAs ,
wikidata:Q27292390 ,
dbr:Netarsudil ,
.
@prefix rdfs: .
dbr:Netarsudil rdfs:label "Netarsudil"@en ,
"\u041D\u0435\u0442\u0430\u0440\u0441\u0443\u0434\u0438\u043B"@ru .
@prefix dct: .
@prefix dbc: .
dbr:Netarsudil dct:subject dbc:Benzoate_esters ,
dbc:Ophthalmology_drugs ,
dbc:Isoquinolines ;
foaf:depiction ,
.
@prefix prov: .
dbr:Netarsudil prov:wasDerivedFrom .
@prefix dbp: .
dbr:Netarsudil dbp:pronounce "ne TAR soo dil"@en ;
foaf:isPrimaryTopicOf wikipedia-en:Netarsudil ;
dbo:wikiPageWikiLink dbr:Blood_plasma ,
dbr:Topical_medication ,
dbr:Elimination_half-life .
@prefix ns13: .
dbr:Netarsudil dbo:wikiPageWikiLink ns13:latanoprost ,
dbr:Methanol ,
dbr:Solubility ,
dbc:Ophthalmology_drugs ,
dbr:Cornea ,
dbc:Isoquinolines ,
dbr:Conjunctiva ,
dbr:First-in-class_medication ,
dbr:European_Medicines_Agency ,
dbr:Active_metabolite ,
dbr:Rho_kinase ,
dbr:Episcleral_layer ,
dbr:Ophthalmic_drug_administration ,
dbr:Hyperaemia ,
dbr:Norepinephrine_transporter ,
dbr:Hygroscopic ,
dbr:Mesilate ,
,
dbr:Trabecular_meshwork ,
dbr:Food_and_Drug_Administration ,
dbr:Intraocular_pressure ,
dbr:Aqueous_humor ,
dbc:Benzoate_esters ,
dbr:Cornea_verticillata ,
dbr:Glaucoma ,
dbr:Ocular_hypertension ,
dbr:Esterase ,
dbr:Hypersensitivity ;
dbo:description "gemyske ferbining"@fy ,
"\u0D30\u0D3E\u0D38\u0D38\u0D02\u200C\u0D2F\u0D41\u0D15\u0D4D\u0D24\u0D02"@ml ,
"senyawa kimia"@in ,
"\u0445\u0456\u043C\u0456\u0447\u043D\u0430\u0435 \u0437\u043B\u0443\u0447\u044D\u043D\u043D\u0435"@be ,
"kemisk forbindelse"@da ,
"cumpostu ch\u00ECmicu"@scn ,
"konposatu kimiko"@eu ,
"chemiese verbinding"@af ,
"composto chimico"@it ,
"\u03C7\u03B7\u03BC\u03B9\u03BA\u03AE \u03AD\u03BD\u03C9\u03C3\u03B7"@el ,
"compuestu qu\u00EDmicu"@ast ,
"compositum chemicum"@la ,
"chemick\u00E1 zl\u00FA\u010Denina"@sk ,
"chemische verbinding"@nl ,
"chemical compound"@en ,
"compost qu\u00EDmic"@ca ,
"compos\u00E9 chimique"@fr ,
"\u0645\u0631\u0643\u0628 \u0643\u064A\u0645\u064A\u0627\u0626\u064A"@ar ,
"compuesto quimico"@an ,
"\u0B0F\u0B39\u0B3E \u0B0F\u0B15 \u0B14\u0B37\u0B27 \u0B2F\u0B3E\u0B39\u0B3E \u0B13\u0B2A\u0B28\u0B4D \u0B06\u0B19\u0B4D\u0B17\u0B32\u0B4D \u0B17\u0B4D\u0B32\u0B15\u0B4B\u0B2E\u0B3E \u0B38\u0B2E\u0B47\u0B24 \u0B2C\u0B30\u0B4D\u0B26\u0B4D\u0B27\u0B3F\u0B24 \u0B07\u0B23\u0B4D\u0B1F\u0B4D\u0B30\u0B3E\u0B13\u0B15\u0B41\u0B32\u0B3E\u0B30 \u0B1A\u0B3E\u0B2A\u0B30 \u0B1A\u0B3F\u0B15\u0B3F\u0B24\u0B4D\u0B38\u0B3E \u0B2A\u0B3E\u0B07\u0B01 \u0B2C\u0B4D\u0B5F\u0B2C\u0B39\u0B43\u0B24 \u0B39\u0B41\u0B0F \u0964"@or ,
"chemick\u00E1 slou\u010Denina"@cs ,
"\u0445\u0435\u043C\u0438\u0441\u043A\u043E \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435"@mk ,
"kemia kombina\u0135o"@eo ,
"compus chimic"@ro ,
"\u5316\u5408\u7269"@zh ,
"compuesto qu\u00EDmico"@es ,
"kemiala kompozajo"@io ,
"\u5316\u5408\u7269"@yue ,
"composito chimic"@ia ,
"keemiline \u00FChend"@et ,
"\u09B0\u09BE\u09B8\u09BE\u09AF\u09BC\u09A8\u09BF\u0995 \u09AF\u09CC\u0997"@bn ,
"\u0584\u056B\u0574\u056B\u0561\u056F\u0561\u0576 \u0574\u056B\u0561\u0581\u0578\u0582\u0569\u0575\u0578\u0582\u0576"@hy ,
"component quimic"@oc ,
"\u0C13\u0C2A\u0C46\u0C28\u0C4D-\u0C2F\u0C3E\u0C02\u0C17\u0C3F\u0C32\u0C4D \u0C17\u0C4D\u0C32\u0C3E\u0C15\u0C4B\u0C2E\u0C3E\u0C24\u0C4B \u0C38\u0C39\u0C3E \u0C2A\u0C46\u0C30\u0C3F\u0C17\u0C3F\u0C28 \u0C15\u0C02\u0C1F\u0C3F\u0C32\u0C4B\u0C2A\u0C32\u0C3F \u0C12\u0C24\u0C4D\u0C24\u0C3F\u0C21\u0C3F\u0C15\u0C3F \u0C1A\u0C3F\u0C15\u0C3F\u0C24\u0C4D\u0C38 \u0C1A\u0C47\u0C2F\u0C21\u0C3E\u0C28\u0C3F\u0C15\u0C3F \u0C09\u0C2A\u0C2F\u0C4B\u0C17\u0C3F\u0C02\u0C1A\u0C47 \u0C12\u0C15 \u0C14\u0C37\u0C27\u0C02"@te ,
"\u0445\u0438\u043C\u0438\u0447\u0435\u0441\u043A\u043E\u0435 \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435"@ru ,
"composto qu\u00EDmico"@gl ,
"\u0445\u0456\u043C\u0456\u0447\u043D\u0430 \u0441\u043F\u043E\u043B\u0443\u043A\u0430"@uk ,
"cyfansoddyn cemegol"@cy ,
"\u0445\u0438\u043C\u0438\u0447\u043D\u043E \u0441\u044A\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435"@bg ,
"komponim kimik"@sq ,
"chemische Verbindung"@de ,
"\u0137\u012Bmisks savienojums"@lv ,
"zwi\u0105zek chemiczny"@pl ,
"composto qu\u00EDmico"@pt ,
"kemiallinen yhdiste"@fi ,
"cheemesch Verbindung"@lb ,
"kjemisk sambinding"@nn ,
"\u05EA\u05E8\u05DB\u05D5\u05D1\u05EA"@iw .
@prefix dbt: .
dbr:Netarsudil dbp:wikiPageUsesTemplate dbt:Portal_bar ,
dbt:Infobox_drug ,
dbt:Clear_left ,
dbt:Short_description ,
dbt:Reflist ,
dbt:Antiglaucoma_preparations_and_miotics ,
,
dbt:Use_dmy_dates ,
dbt:Cite_web ;
dbp:legalEu "Rx-only"@en ;
dbp:legalUs "Rx-only"@en ;
dbp:dailymedid "Netarsudil"@en ;
dbp:drugbank "DB13931"@en ;
dbo:drugbank "DB13931" ;
dbp:medlineplus "a618014"@en ;
dbo:medlinePlus "a618014" .
@prefix dbd: .
dbr:Netarsudil dbp:eliminationHalfLife "-61200.0"^^dbd:second ;
dbp:metabolism "Esterases in the cornea"@en ;
dbp:index2Label "as salt"@en ;
dbp:atcSuffix "EX05"@en ;
dbp:routesOfAdministration dbr:Topical_medication ,
dbr:Ophthalmic_drug_administration ;
dbp:tradename "Rhopressa, Rhokiinsa"@en ;
dbo:alternativeName "Rhopressa, Rhokiinsa"@en ;
dbp:synonyms "AR-13324"@en .
@prefix ns16: .
dbr:Netarsudil dbo:wikiPageExternalLink ns16:netarsudil ,
;
dbp:stdinchi 1 ;
dbp:smiles "Cc1cccCOCc2ccc[C@@H]CNc3ccc4cnccc4c3"@en ;
dbp:c 28 ;
dbp:pubchem 66599893 ;
dbp:stdinchikey "OURRXQUGYQRVML-AREMUKBSSA-N"@en ;
dbp:o 3 ;
dbo:casNumber "1254032-66-0" ;
dbp:n 3 ;
dbp:atcPrefix "S01"@en ;
dbp:casNumber 1254032 ;
dbp:iupacName "[4-[-3-Amino-1--1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate"@en ;
dbp:h 27 ;
dbp:chemspiderid 34980598 ;
dbo:pubchem "66599893" ;
dbp:metabolites "AR-13503"@en ;
dbp:licenceEu "yes"@en ;
dbo:kegg "D11030" ,
"D11031" ;
dbp:kegg "D11030"@en ,
"D11031"@en ;
dbo:thumbnail ;
dbo:fdaUniiCode "W6I5QDT7QI" ;
dbp:unii "W6I5QDT7QI"@en ;
dbp:durationOfAction "86400.0"^^dbd:second .
dbr:Netarsudil_mesylate dbo:wikiPageWikiLink dbr:Netarsudil ;
dbo:wikiPageRedirects dbr:Netarsudil .
dbr:Netarsudil_dimesylate dbo:wikiPageWikiLink dbr:Netarsudil ;
dbo:wikiPageRedirects dbr:Netarsudil .
dbr:C28H27N3O3 dbo:wikiPageWikiLink dbr:Netarsudil ;
dbo:wikiPageRedirects dbr:Netarsudil .
dbr:Rhokiinsa dbo:wikiPageWikiLink dbr:Netarsudil ;
dbo:wikiPageRedirects dbr:Netarsudil .
dbr:Rhopressa dbo:wikiPageWikiLink dbr:Netarsudil ;
dbo:wikiPageRedirects dbr:Netarsudil .